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Crosstalk between gut microbiome and immunology in the management of ischemic brain injury

Crosstalk between gut microbiome and immunology in the management of ischemic brain injury

Ischemic brain injury is a severe neurological complication, which accrues an immense activation of neuroinflammatory responses. Several strains of analysis steered the interconnection of gut microbiota perturbation with the activation of proinflammatory mediators. Intestinal microbial communities additionally interchange info with the brain by varied afferent and efferent channels and microbial by-products. Herein, we focus on …

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The potential use of lactate blockers for the prevention of COVID-19 worst outcome, insights from exercise immunology

The potential use of lactate blockers for the prevention of COVID-19 worst outcome, insights from exercise immunology

Following the decline in Physical Activity (PA) because of COVID-19 restrictions in the kind of authorities mandated lockdowns and closures of public areas, the modulatory impact of bodily exercise on immunity is being closely revisited. In an try to grasp the broad discrepancy in affected person response to COVID-19 and the elements that doubtlessly modulate …

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Editorial: COVID-19 immunology and organ transplantation

Editorial: COVID-19 immunology and organ transplantation

The goal of this research was to supply a crucial appraisal of the literature on the consequences of the COVID-19 pandemic on organ transplantation, with a particular concentrate on lung transplantation given the predominant pulmonary involvement of the virus. There was a big lower in lung transplant volumes in the course of the first wave of …

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